IAM.PC

IAM.PC is for simplified protein isolation and purification, allowing for rapid purification of membrane proteins while maintaining biological activity. The phase is based on the membrane lipid, Phosphatidylcholine (PC), and consists of monolayers of amphiphilic phospholipids covalently bonded to aminopropyl silica through a terminal amide linkage. As a result, the bulky phosphatidylcholine groups shield many of the amine binding sites on the silica surface, preventing amine interaction with the protein molecules.

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Selector/Phase Type:

Phosphatidylcholine covalently bonded to aminopropyl silica

Techniques:

High Performance Liquid Chromatography (HPLC)