The inner and outer surfaces of the SPS are bonded separately, allowing each to be varied independently. The C18 structure includes an ODS hydrophobic inner phase, which allows for separation of small analytes. The hydrophilic outer phase of polyethylene glycol provides size exclusion and hydrophilic shielding, which repels large biomolecules.
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Mixed Mode: Size Exclusion/C18
High Performance Liquid Chromatography (HPLC)
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