Packed with the Ester PC Ligand phase, IAM Fast-Screen Mini columns are a rapid and economically viable screening method for the high throughput estimation of drug permeability. This can be of great use in characterizing large libraries of compounds.
The 1 cm Fast-Screen Mini Column is offered not as a separation tool, but rather as a tool for characterizing the chromatographic retention factor (k’) of individual analytes. The measured k’ of analytes on this column can be used to estimate a value for drug permeability.
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Ester Phosphatidylcholine Ligand
High Performance Liquid Chromatography (HPLC)
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